The thawing of Arctic permafrost is endangering the lives of up to three million people, disrupting infrastructure, transportation, and supplies. Harmful substances released by thawing exacerbate health and environmental issues. Indigenous communities face erosion, landslides, and changed lifestyles, yet remain hopeful due to historical resilience. Researchers highlight potential threats to water, food, and health from climate-induced changes, as documented in a detailed study involving affected populations across Europe, America, and Asia.