The catastrophic wildfires in Los Angeles have resulted in 24 fatalities, with significant long-term health implications expected due to toxic smoke exposure. The Eaton and Palisades Fires, ranked among California's deadliest, highlight the severe health impacts of wildfire particulate pollution. Wildfire smoke's PM2.5 particles increase risks of cardiovascular and respiratory illnesses, contributing to thousands of premature deaths annually. Studies predict increased mortality and economic damages from wildfire smoke due to climate change, exacerbating these issues globally. The recent fires have exposed millions to hazardous air quality, with additional health burdens likely from communi- cable diseases among displaced populations. Similar to hurricanes, health complications and excess mortality could persist for years due to economic disruption, social changes, and stress.